Co-infection with hepatitis C increases the risk of death for patients with AIDS by 50%, according to the results of a large study published in the online edition of Clinical Infectious Diseases. A fifth of these deaths were attributable to liver-related causes, five times the rate seen in people with AIDS who were not co-infected.
The investigators also found that a third of co-infected patients were unaware of their hepatitis C infection.
The Food and Drug Administration warned Friday that doctors should not prescribe and patients should not use the hepatitis C drug Victrelis (boceprevir) and the anti-HIV drug ritonavir at the same time because such use reduces the effectiveness of both drugs.